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Posts Tagged ‘schwab’

To AI: Is the cavum septum pellucidum unique to psychopaths?

Posted in General, tagged , , , , , , , , , , , , , , on August 17, 2025| 3 Comments »

No—its presence alone doesn’t single out psychopaths. 

  • Prevalence in the general population is ~5–20 % depending on age, sex, scan resolution, and diagnostic criteria used. 
  • Meta-analysis of forensic samples (Boccardi et al., 2010; Schiffer et al., 2013) finds CSP enlarged (>6 mm) in roughly one-third to one-half of high-scoring PCL-R psychopaths, which is statistically higher than community samples but leaves the majority of non-criminals—and a substantial minority of psychopaths—without it. 
  • Traumatic brain injury, schizophrenia, bipolar disorder, autism, and even normal variants also show CSP overlap; therefore its specificity for psychopathy is low. 

So while an enlarged CSP may correlate with psychopathy in some forensic cohorts, it is neither necessary nor sufficient for diagnosis and is far from unique to psychopaths.

Hmmm.

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John Wayne Gacy’s brain

Posted in General, tagged , , , , , , , , , , , on April 14, 2024| Leave a Comment »

Dr. Helen Morrison displays sections of John Wayne Gacy’s brain April 29, 2004. | AP

https://chicago.suntimes.com/2018/12/14/18416340/where-john-wayne-gacy-buried-the-bodies-more-key-sites-tied-to-serial-killer

https://www.alamy.com/slices-of-john-wayne-gacys-brain-displayed-by-serial-killer-expert-dr-helen-morrison-dr-helen-louise-morrison-1942-an-american-forensic-psychiatrist-and-writer-john-wayne-gacy-jr-1942-1994-an-american-serial-killer-and-rapist-during-the-1970s-image328357534.html

Note the top brain slice, specifically the butterfly shaped hole and the brain structure dividing the two halves, the pellucidum septum.  The septum is divided in the middle by an opening, the cavum.

From my https://pathwhisperer.info/2014/12/09/psychopathy-marker-neurodevelopmental-marker-for-limbic-maldevelopment-in-antisocial-personality-disorder-and-psychopathy/:

Psychopathy marker — “Neurodevelopmental marker for limbic maldevelopment in antisocial personality disorder and psychopathy”

braindifferences

“Illustration of normal septum pellucidum (thin membrane separating the lateral ventricles) in a non-antisocial control (a) and the cavum septum pellucidum in an individual with antisocial personality disorder (b).

Coronal magnetic resonance image slices are at the level of the head of the anterior limb of the internal capsule, caudate, putamen, accumbens, and insula. Highlighted within the bue box is the septum pellucidum, dividing the lateral ventricles and bordered superiorly by the body of the corpus callosum and inferiorly by the fornix. The normal control (a) shows a fused septum pellucidum, whereas the participant with antisocial personality disorder (b) shows a fluid-filled cavum inside the two leaflets of the septum pellucidum.”

http://bjp.rcpsych.org/content/197/3/186/F1.expansion

Oh Fauci, Collins, Bancel, Schwab, Sahin . . . yoo hoo . . .

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